Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643712 | 1.00 | ESR1 (0.47) | ESR1ESR2PKMALDH1A1DPP4 | |
| SCHEMBL20995813 | 0.83 | ESR1 (0.51) | ESR1ESR2PKMMEN1KMT2A | |
| SCHEMBL20995812 | 0.83 | ESR1 (0.51) | ESR1ESR2PKMMEN1KMT2A | |
| SCHEMBL4683432 | 0.82 | ESR1 (0.54) | ESR1ESR2PKMALDH1A1DPP4 | |
| SCHEMBL4683430 | 0.82 | ESR1 (0.54) | ESR1ESR2PKMALDH1A1DPP4 | |
| SCHEMBL19643709 | 0.77 | ESR1 (0.46) | ESR1ESR2PKMALDH1A1MEN1 | |
| SCHEMBL19643014 | 0.76 | ESR1 (0.47) | ESR1ESR2PKMALDH1A1DPP4 | |
| SCHEMBL31680211 | 0.76 | ESR1 (0.47) | ESR1ESR2PKMALDH1A1DPP4 | |
| SCHEMBL757937 | 0.72 | CYP3A4 (0.51) | ESR1PKMDPP4CYP3A4HSD17B1 | |
| SCHEMBL757936 | 0.72 | CYP3A4 (0.51) | ESR1PKMDPP4CYP3A4HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3463362-B1 | SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME LLC (US) | 2025-09-03 | — | — | EP | disclosed |