SCHEMBL31681982

SCHEMBL31681982

O=C(O)CCCCCCCCCCCCCCCc1cc(Oc2ccc(S(=O)(=O)Nc3ncc(C(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)O)cn3)cc2)ccc1F

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC9A3 P48764 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
PKM P14618 1/20 0.35
SQSTM1 Q13501 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TBXAS1 P24557 5/20 0.34
TDP1 Q9NUW8 1/20 0.34
EGLN2 Q96KS0 3/20 0.34
EGLN1 Q9GZT9 2/20 0.34
FABP1 P07148 1/20 0.34
GAA P10253 1/20 0.34
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22029371 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL22080213 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL22080206 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL31682093 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL22080451 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL24257949 1.00 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL24257877 0.96 SLC9A3 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL24257845 0.93 SLC9A3 (0.38) SLC9A3SMN1; SMN2PKMTDP1
SCHEMBL22080217 0.92 SLC22A12 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1
SCHEMBL22029404 0.92 SLC22A12 (0.37) SLC9A3SMN1; SMN2PKMSQSTM1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 EP disclosed