Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167382 | 0.88 | S1PR1 (0.33) | GRM2S1PR1S1PR3S1PR5FFAR4 | |
| SCHEMBL6059627 | 0.86 | S1PR1 (0.32) | GRM2S1PR1S1PR3S1PR5 | |
| SCHEMBL3965501 | 0.84 | S1PR1 (0.32) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3166692 | 0.83 | FFAR4 (0.35) | S1PR1S1PR3S1PR5GRIN2BFFAR4 | |
| SCHEMBL6059952 | 0.82 | S1PR1 (0.31) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3158249 | 0.82 | ESR1 (0.31) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3168450 | 0.82 | FFAR4 (0.34) | GRM2S1PR1S1PR3S1PR5GRIN2B | |
| SCHEMBL3172954 | 0.81 | CYP17A1 (0.34) | GRM2S1PR1S1PR3S1PR5GRIN2B | |
| SCHEMBL3158571 | 0.79 | ERN1 (0.38) | ERN1 | |
| SCHEMBL3167675 | 0.78 | RARB (0.41) | ERN1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452514-B1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK & CHEMICALS (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-1273562-B1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK & CHEMICALS (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-0952135-A1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-10-27 | — | — | EP | disclosed |