SCHEMBL31684786

SCHEMBL31684786

C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2)ncc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SRC P12931 13/20 1.00
MAP3K7 O43318 12/20 1.00
FGFR1 P11362 9/20 1.00
MAP2K1 Q02750 4/20 1.00
MAPK1 P28482 3/20 1.00
FLT3 P36888 1/20 0.77
HCK P08631 1/20 0.75
EGFR P00533 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22828520 1.00 SRC (1.00) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807490 0.91 SRC (0.83) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL28980984 0.90 SRC (0.82) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807493 0.90 SRC (0.82) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807377 0.90 SRC (0.82) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL28980965 0.90 MAP3K7 (0.81) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807404 0.90 MAP3K7 (0.81) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807443 0.90 MAP3K7 (0.83) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL22807452 0.89 SRC (0.81) SRCMAP3K7FGFR1MAP2K1MAPK1
SCHEMBL31684777 0.89 MAP3K7 (0.80) SRCMAP3K7FGFR1MAP2K1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4617261-A1 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Wenzhou Medical University (CN) 2025-09-17 EP claimed