Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 3/20 | 0.70 |
| ▸ | BRD4 | O60885 | 9/20 | 0.67 |
| ▸ | FLT3 | P36888 | 2/20 | 0.65 |
| ▸ | BTK | Q06187 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.64 |
| ▸ | CTSC | P53634 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28698547 | 0.85 | BRD4 (0.78) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL29514718 | 0.85 | BRD4 (0.78) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL28711724 | 0.84 | BRD4 (0.73) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL28876191 | 0.84 | BRD4 (0.79) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL29390384 | 0.84 | BRD4 (0.73) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL28980992 | 0.83 | BRD4 (0.72) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL29793826 | 0.82 | EGFR (0.79) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL26394684 | 0.82 | EGFR (0.79) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL12952140 | 0.82 | SYK (0.68) | SYKEGFRBRD4FLT3BTK | |
| SCHEMBL657089 | 0.82 | SYK (1.00) | SYKFLT3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | disclosed |