Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29212747 | 1.00 | TP53 (0.54) | TP53PDE5APDE9AMETAP2MAPT | |
| SCHEMBL24098518 | 0.81 | DAO (0.47) | TP53 | |
| SCHEMBL29078234 | 0.81 | DAO (0.47) | TP53MAPTCHEK1 | |
| SCHEMBL30576717 | 0.81 | DAO (0.47) | TP53MAPTCHEK1 | |
| SCHEMBL30902525 | 0.81 | PARP1 (0.41) | TP53PDE5APDE9AAURKAPRKD3 | |
| SCHEMBL30896193 | 0.79 | PDE9A (0.36) | TP53PDE5APDE9ACDK5CDK5R1 | |
| SCHEMBL31386723 | 0.78 | CDK5 (0.40) | TP53PDE5APDE9AMAPTAURKA | |
| SCHEMBL29203506 | 0.78 | PARP1 (0.46) | MAPTAURKA | |
| SCHEMBL30273161 | 0.78 | PARP1 (0.39) | PDE5APDE9AAURKAPRKD3MAP4K4 | |
| SCHEMBL30273139 | 0.78 | PARP1 (0.41) | PDE9AAURKACDK5PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617273-A1 | FUSED TRICYCLIC PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Haihe Biopharma Co., Ltd. (CN) | 2025-09-17 | — | — | EP | disclosed |