Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687316 | 0.92 | MC4R (0.82) | MC4RKCNH2NOS1NOS2SYK | |
| SCHEMBL25276740 | 0.90 | MC4R (0.83) | MC4RKCNH2 | |
| SCHEMBL30457637 | 0.90 | MC4R (0.83) | MC4RKCNH2 | |
| SCHEMBL25227171 | 0.90 | MC4R (0.83) | MC4RKCNH2 | |
| SCHEMBL30457504 | 0.90 | MC4R (0.83) | MC4RKCNH2 | |
| SCHEMBL30996498 | 0.84 | MC4R (0.67) | MC4RKCNH2 | |
| SCHEMBL30996497 | 0.82 | MC4R (0.86) | MC4RKCNH2 | |
| SCHEMBL31666900 | 0.82 | MC4R (0.79) | MC4RKCNH2SYK | |
| SCHEMBL31421679 | 0.82 | MC4R (0.86) | MC4RKCNH2SYK | |
| SCHEMBL31666908 | 0.82 | MC4R (0.66) | MC4RKCNH2JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620955-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |