Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.63 |
| ▸ | CKS1B | P61024 | 2/20 | 0.53 |
| ▸ | SKP1 | P63208 | 2/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912745 | 0.97 | ACKR3 (0.66) | ACKR3CKS1BSKP1SKP2HPGDS | |
| SCHEMBL3543198 | 0.82 | HTR2C (0.63) | MEN1KMT2AHTR2CPTGDR2PIN1 | |
| SCHEMBL29944217 | 0.82 | HTR2C (0.63) | MEN1KMT2AHTR2CPTGDR2PIN1 | |
| SCHEMBL3547467 | 0.82 | HTR2C (0.63) | MEN1KMT2AHTR2CPTGDR2PIN1 | |
| SCHEMBL2142176 | 0.81 | CHRM2 (0.54) | ACKR3HPGDSSCD5HTR2C | |
| SCHEMBL22221788 | 0.80 | PTGDR2 (0.53) | ACKR3HPGDSHTR2CPTGDR2PIN1 | |
| SCHEMBL2225857 | 0.80 | HDAC1 (0.55) | HPGDSHTR2CPTGDR2PIN1HDAC1 | |
| SCHEMBL12962315 | 0.79 | KMT2A (0.57) | MEN1KMT2APOLB | |
| SCHEMBL22221684 | 0.79 | ACKR3 (0.71) | ACKR3CKS1BSKP1SKP2 | |
| SCHEMBL22221831 | 0.79 | PTGDR2 (0.52) | ACKR3HPGDSHTR2CPTGDR2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4620949-A1 | ACKR3 MODULATORS FOR CARDIOVASCULAR OR ANTIPLATELET THERAPY | Eberhard Karls Universität Tübingen (Medizinische Fakultät) (DE) | 2025-09-24 | — | — | EP | disclosed |