Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 6/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16802992 | 0.85 | EPHX2 (0.54) | ALDH1A1LMNAEPHX2ABCC4MAPT | |
| SCHEMBL23065435 | 0.81 | EPHX2 (0.61) | ALDH1A1LMNAEPHX2ABCC4MAPT | |
| SCHEMBL1834688 | 0.80 | EPHX2 (0.53) | ALDH1A1EPHX2KDM4AKDM4CCNR1 | |
| SCHEMBL23732698 | 0.80 | KDM4A (0.46) | ALDH1A1EPHX2KDM4AKDM4CBCHE | |
| SCHEMBL1830915 | 0.80 | EPHX2 (0.53) | ALDH1A1EPHX2KDM4AKDM4CCNR1 | |
| SCHEMBL23732848 | 0.80 | EPHX2 (0.53) | ALDH1A1EPHX2KDM4AKDM4CCNR1 | |
| SCHEMBL1837811 | 0.80 | EPHX2 (0.53) | ALDH1A1EPHX2KDM4AKDM4CCNR1 | |
| SCHEMBL1832887 | 0.80 | EPHX2 (0.53) | ALDH1A1EPHX2KDM4AKDM4CCNR1 | |
| SCHEMBL3112105 | 0.79 | MAPT (0.57) | ALDH1A1LMNAEPHX2ABCC4MAPT | |
| SCHEMBL3112734 | 0.79 | MAPT (0.57) | ALDH1A1LMNAEPHX2ABCC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817109-B1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-7648636-B2 | A chromatographic support including an immobilized ligand which combines an anion-exchange domain comprising an oligocyclic aza compound with endocyclic nitrogen and a non-ionic, second binding domain to allow adjustment of the overall hydrophobicity/hydrophilicity; separation; purification; peptides | MERCK PATENT GMBH (DE) | 2010-01-19 | — | — | US | disclosed |
| US-20080164211-A1 | Mixed-Modal Anion-Exchanged Type Separation Material | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1817109-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | Merck Patent GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1693108-A1 | Mixed-modal anion-exchange type separation material | MERCK PATENT GmbH (DE) | 2006-08-23 | — | — | EP | disclosed |
| WO-2006058623-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |