SCHEMBL31691367

SCHEMBL31691367

COC(=O)c1ccc(Cn2cccn2)c(C2CCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KAT7 O95251 3/20 0.43
▸ KAT6A Q92794 3/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ HTT P42858 2/20 0.43
▸ KAT6B Q8WYB5 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ HDAC1 Q13547 1/20 0.41
▸ HDAC6 Q9UBN7 1/20 0.41
▸ HRH3 Q9Y5N1 3/20 0.41
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CNR1 P21554 1/20 0.39
▸ CNR2 P34972 1/20 0.39
▸ TSHR P16473 1/20 0.38
▸ KAT5 Q92993 1/20 0.37
▸ KAT8 Q9H7Z6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31172731 0.96 KAT7 (0.46) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31691486 0.88 HDAC1 (0.40) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31691464 0.86 HTT (0.53) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31691311 0.86 HDAC1 (0.40) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31689713 0.83 HTT (0.52) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31172740 0.82 HTT (0.55) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31691286 0.80 HDAC1 (0.44) KMT2AMEN1NPSR1HTTGAA
SCHEMBL17221669 0.79 KLKB1 (0.50) KMT2AMEN1KAT7KAT6AHTT
SCHEMBL553315 0.79 KLKB1 (0.47) KMT2AMEN1KAT7KAT6ANPSR1
SCHEMBL31691302 0.79 HDAC1 (0.46) KMT2AMEN1NPSR1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed
WO-2025201504-A1 KAT6 INHIBITORS BEIGENE (SUZHOU) CO., LTD. (CN) 2025-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A KMT2A 68/4885MEN1 3836/4885KAT7 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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