SCHEMBL31691405

SCHEMBL31691405

COc1ccc(C(C)(C)C)nc1S(=O)(=O)NC(=O)c1ccc(Cn2cccn2)c(C2CC2)n1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 12/20 0.39
▸ KAT6A Q92794 12/20 0.39
▸ KAT6B Q8WYB5 8/20 0.39
▸ KAT5 Q92993 5/20 0.39
▸ KAT8 Q9H7Z6 5/20 0.39
▸ MAPT P10636 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ NPSR1 Q6W5P4 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ KLKB1 P03952 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691304 0.89 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691277 0.86 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691261 0.86 KAT7 (0.43) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691361 0.86 KAT7 (0.36) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31172522 0.84 KAT7 (0.52) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691325 0.84 KAT7 (0.34) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691480 0.83 KAT7 (0.42) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691398 0.83 KAT7 (0.43) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691319 0.82 KAT7 (0.44) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691344 0.81 KAT7 (0.42) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed
WO-2025201504-A1 KAT6 INHIBITORS BEIGENE (SUZHOU) CO., LTD. (CN) 2025-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A KAT7 4/4885KAT6A 1/4885KAT6B 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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