Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16893987 | 0.94 | KDM4E (0.36) | KDM4EHDAC4 | |
| SCHEMBL16896779 | 0.78 | KDM4E (0.54) | KDM4E | |
| SCHEMBL6123996 | 0.73 | KDM4E (0.38) | KDM4E | |
| SCHEMBL3792647 | 0.73 | KDM4E (0.38) | KDM4EHDAC4 | |
| SCHEMBL16893991 | 0.72 | KDM4E (0.33) | KDM4EHDAC4 | |
| SCHEMBL15677034 | 0.71 | AR (0.40) | — | |
| SCHEMBL16866861 | 0.71 | BRD4 (0.46) | KDM4E | |
| SCHEMBL31694125 | 0.71 | BRD4 (0.46) | KDM4E | |
| SCHEMBL9343747 | 0.69 | KDM4E (0.37) | KDM4E | |
| SCHEMBL13543883 | 0.68 | KDM4E (0.39) | KDM4EHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |