Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701841 | 0.93 | DDB1 (0.48) | DDB1CRBNPIK3CAMTORALDH1A1 | |
| SCHEMBL31701823 | 0.85 | DDB1 (0.48) | DDB1CRBNALDH1A1CHRM2OPRM1 | |
| SCHEMBL31702237 | 0.84 | DDB1 (0.42) | DDB1CRBNPIK3CA | |
| SCHEMBL31700714 | 0.83 | DDB1 (0.52) | DDB1CRBNPIK3CAMTORBMPR1A | |
| SCHEMBL29768057 | 0.81 | CRBN (0.55) | DDB1CRBNBMPR1AACVRL1ACVR1 | |
| SCHEMBL29079616 | 0.81 | CRBN (0.55) | DDB1CRBNBMPR1AACVRL1ACVR1 | |
| SCHEMBL30574621 | 0.80 | DDB1 (0.43) | DDB1CRBNBMPR1AACVRL1ACVR1 | |
| SCHEMBL29079567 | 0.80 | DDB1 (0.43) | DDB1CRBNBMPR1AACVRL1ACVR1 | |
| SCHEMBL31700605 | 0.79 | DDB1 (0.43) | DDB1CRBNPIK3CAMTOR | |
| SCHEMBL21998101 | 0.78 | DDB1 (0.58) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885PIK3CA 2223/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885PIK3CA 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.