Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31702313 | 0.86 | DDB1 (0.51) | DDB1CRBNMAPK14PIK3CAMTOR | |
| SCHEMBL31700714 | 0.80 | DDB1 (0.52) | DDB1CRBNPIK3CAMTORWNT1 | |
| SCHEMBL23832588 | 0.79 | CRBN (0.67) | DDB1CRBN | |
| SCHEMBL20840319 | 0.78 | DDB1 (0.47) | DDB1CRBNCYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL30893224 | 0.78 | CRBN (0.66) | DDB1CRBN | |
| SCHEMBL20845729 | 0.77 | DDB1 (0.52) | DDB1CRBNCYP1A2CYP1B1 | |
| SCHEMBL29700857 | 0.77 | DDB1 (0.52) | DDB1CRBNCYP1A2CYP1B1 | |
| SCHEMBL22836090 | 0.77 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL22526122 | 0.76 | CRBN (0.69) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL30043700 | 0.76 | DDB1 (0.63) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | DDB1 3966/4885CRBN 1627/4885CYP1A2 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.