SCHEMBL31702908

SCHEMBL31702908

C[C@H]1C[C@@H]1c1cc(C(N)=O)c[nH]c1=O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NNMT P40261 3/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
CDC7 O00311 1/20 0.36
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31
MAPKAPK2 P49137 1/20 0.31
ALDH1A1 P00352 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31702895 0.79 CDC7 (0.38) NNMTHTR1DHTR1BCDC7
SCHEMBL30647258 0.72 HTR1D (0.34) HTR1DHTR1BCDC7
SCHEMBL3744449 0.71 CDC7 (0.42) CDC7BRD4ALDH1A1NOTUM
SCHEMBL31702816 0.71 F2 (0.38) HTR1DHTR1BCDC7
SCHEMBL18584787 0.70 CDC7 (0.36) NNMTCDC7ALDH1A1NOTUM
SCHEMBL18696150 0.69 CDC7 (0.43) HTR1DHTR1BCDC7ALDH1A1NOTUM
SCHEMBL31702823 0.67 CDC7 (0.36) CDC7ALDH1A1NOTUM
SCHEMBL16168454 0.66
SCHEMBL18584659 0.65 DPP4 (0.39) HTR1DHTR1BCDC7BRD4
SCHEMBL18584634 0.65 BRD4 (0.43) CDC7BRD4CREBBPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217420-A1 PYRIDINONE COMPOUNDS, METHODS AND USES THEREOF ZENO MANAGEMENT, INC. (US) 2025-10-16 WO disclosed