Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.74 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516978 | 1.00 | PIK3CA (0.74) | PIK3CAMAPK13PIK3CBHRH3KDM4E | |
| SCHEMBL3750019 | 0.86 | HRH3 (0.57) | PIK3CAHRH3KDM4EKDM6BKDM5C | |
| SCHEMBL4725584 | 0.85 | PIK3CA (0.70) | PIK3CAMAPK13KDM4ERAB9AALDH1A1 | |
| SCHEMBL19672049 | 0.85 | PIK3CA (0.56) | PIK3CAMAPK13PIK3CBHRH3KDM4E | |
| SCHEMBL12639899 | 0.84 | PIK3CA (0.76) | PIK3CAMAPK13KDM4ERAB9AALDH1A1 | |
| SCHEMBL2028882 | 0.84 | PIK3CA (0.57) | PIK3CAHRH3KDM4EKDM6BKDM5C | |
| SCHEMBL5929302 | 0.84 | PIK3CA (0.54) | PIK3CAMAPK13HRH3KDM4EKDM6B | |
| SCHEMBL17843238 | 0.83 | HRH3 (0.54) | PIK3CAHRH3KDM4EKDM6BKDM5C | |
| SCHEMBL1021177 | 0.83 | HRH3 (0.54) | PIK3CAHRH3KDM4EKDM6BKDM5C | |
| SCHEMBL13702422 | 0.83 | PIK3CA (0.70) | PIK3CAMAPK13ADORA2AADORA1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |