Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CIT | O14578 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30913861 | 0.78 | PDE2A (0.60) | PDE2ACASRAKR1C3AKR1C2ADRB2 | |
| SCHEMBL268077 | 0.76 | PDE2A (0.67) | PDE2ACASRHTR2AHTR2CHTR2B | |
| SCHEMBL701658 | 0.76 | PDE2A (0.67) | PDE2ACASRHTR2AHTR2CHTR2B | |
| SCHEMBL335039 | 0.76 | PDE2A (0.67) | PDE2ACASRHTR2AHTR2CHTR2B | |
| Bromide SCHEMBL28801001 | 0.74 | PDE2A (0.64) | PDE2ACASRAKR1C3AKR1C2HTR2A | |
| Hydrochloric Acid SCHEMBL4935636 | 0.74 | PDE2A (0.64) | PDE2ACASRHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL20266800 | 0.74 | PDE2A (0.64) | PDE2ACASRHTR2AHTR2CHTR2B | |
| Iodide SCHEMBL28800992 | 0.74 | PDE2A (0.64) | PDE2ACASRAKR1C3AKR1C2HTR2A | |
| Hydrochloric Acid SCHEMBL27940422 | 0.74 | PDE2A (0.64) | PDE2ACASRHTR2AHTR2CHTR2B | |
| SCHEMBL31705346 | 0.73 | AKR1C3 (0.40) | PDE2ACASRAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |