Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106051 | 0.88 | MAPK14 (0.46) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105912 | 0.87 | MAPK14 (0.50) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105893 | 0.86 | LCK (0.41) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105951 | 0.85 | LCK (0.43) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105942 | 0.85 | LCK (0.42) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31106019 | 0.84 | LCK (0.45) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105865 | 0.84 | LCK (0.46) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105905 | 0.83 | MAPK14 (0.41) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105895 | 0.82 | LCK (0.44) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL31105889 | 0.81 | HCK (0.44) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215188-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PKMYT1 | MY-T BIO LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |