Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31705720 | 0.85 | BACE1 (0.40) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL31705337 | 0.79 | SSTR4 (0.46) | BACE1AAK1SSTR4 | |
| SCHEMBL31705371 | 0.78 | BACE1 (0.41) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL21672314 | 0.74 | BACE1 (0.49) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL17966689 | 0.74 | PRMT5 (0.57) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL29633982 | 0.74 | PRMT5 (0.57) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL25146980 | 0.73 | BACE1 (0.44) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL29845293 | 0.73 | BACE1 (0.44) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL26728111 | 0.73 | BACE1 (0.42) | BACE1BACE2AAK1USP30PRMT5 | |
| SCHEMBL21070780 | 0.73 | BACE1 (0.42) | BACE1BACE2AAK1USP30PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |