Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25574986 | 0.84 | PRMT5 (0.46) | PRMT5WDR77CACNA1HCACNA1BCACNA1C | |
| SCHEMBL22664611 | 0.83 | PRMT5 (0.45) | PRMT5WDR77CACNA1HCACNA1BCACNA1C | |
| SCHEMBL5141535 | 0.82 | PRMT5 (0.46) | PRMT5WDR77CACNA1HCACNA1BCACNA1C | |
| SCHEMBL31704619 | 0.82 | PRMT5 (0.46) | PRMT5WDR77CACNA1HCACNA1BCACNA1C | |
| SCHEMBL29840292 | 0.82 | PRMT5 (0.44) | PRMT5WDR77LMNAPOLBAAK1 | |
| SCHEMBL23336679 | 0.82 | PRMT5 (0.44) | PRMT5WDR77LMNAPOLBAAK1 | |
| SCHEMBL24502715 | 0.81 | PRMT5 (0.48) | PRMT5WDR77AAK1RPS6KA1KDM4A | |
| SCHEMBL29903067 | 0.81 | PRMT5 (0.48) | PRMT5WDR77AAK1RPS6KA1KDM4A | |
| SCHEMBL17664633 | 0.81 | PRMT5 (0.45) | PRMT5WDR77CACNA1HCACNA1BCACNA1C | |
| SCHEMBL16794372 | 0.80 | PRMT5 (0.56) | PRMT5WDR77CACNA1HCACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |