Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 15/20 | 0.51 |
| ▸ | JAK1 | P23458 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539476 | 0.77 | JAK3 (0.60) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL4053733 | 0.75 | JAK3 (0.67) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL3538287 | 0.74 | JAK3 (0.59) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL3959598 | 0.72 | LCK (0.70) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL3961817 | 0.71 | JAK3 (0.69) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL19596122 | 0.69 | JAK3 (0.79) | JAK3JAK1 | |
| SCHEMBL2024604 | 0.68 | JAK3 (1.00) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL29767896 | 0.68 | JAK3 (0.49) | JAK3JAK1 | |
| SCHEMBL2016053 | 0.67 | JAK3 (1.00) | JAK3JAK1LCKKITAKT2 | |
| SCHEMBL20125438 | 0.67 | JAK3 (0.95) | JAK3JAK1LCKKITAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217212-A1 | MAC1 INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-16 | — | — | WO | disclosed |