Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.52 |
| ▸ | JAK1 | P23458 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31711647 | 0.91 | TYK2 (0.51) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL29882789 | 0.90 | TYK2 (0.61) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30465864 | 0.84 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL25748683 | 0.84 | TYK2 (0.52) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923150 | 0.82 | TYK2 (0.48) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27295670 | 0.82 | TYK2 (0.48) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27293779 | 0.81 | TYK2 (0.49) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL27298988 | 0.81 | TYK2 (0.48) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923244 | 0.81 | TYK2 (0.48) | TYK2JAK1KCNH2JAK2STAT3 | |
| SCHEMBL30923096 | 0.80 | TYK2 (0.55) | TYK2JAK1KCNH2JAK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637738-A2 | INHIBITORS OF JAK2 | Llydaw Therapeutics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |