SCHEMBL31711898

SCHEMBL31711898

COC(=O)C1(C=O)CCC(OC)(OC)CC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2547049 0.89
SCHEMBL4866927 0.82 NPSR1 (0.35) NPSR1LMNA
SCHEMBL1971946 0.81 NPSR1 (0.42) NPSR1LMNA
SCHEMBL4864227 0.81 NPSR1 (0.47) NPSR1LMNA
SCHEMBL2305290 0.79 NPSR1 (0.45) NPSR1LMNA
SCHEMBL4872719 0.79 NPSR1 (0.45) NPSR1LMNA
SCHEMBL5113321 0.76 CYP3A4 (0.40) NPSR1LMNA
SCHEMBL4863377 0.74 NPSR1 (0.33) NPSR1LMNA
SCHEMBL4863381 0.74 NPSR1 (0.33) NPSR1LMNA
SCHEMBL15564880 0.74 FFAR3 (0.40) NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102383-A1 LPAR1 Inhibitors ABBVIE INC (US) 2026-04-16 US disclosed
WO-2025226510-A1 LPAR1 INHIBITORS ABBVIE INC. (US) 2025-10-30 WO disclosed
EP-4640274-A1 LPAR1 INHIBITORS AbbVie Inc. (US) 2025-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102383-A1 LPAR1 Inhibitors LPAR1, LPAR6, LPAR2 NPSR1 98/4885LMNA 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.