Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 2/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915555 | 1.00 | PDPK1 (0.56) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| SCHEMBL7765657 | 0.83 | PDPK1 (0.51) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| SCHEMBL2730455 | 0.80 | PDPK1 (0.56) | PDPK1GDADPP4PI4KAPI4K2B | |
| Sulfuric Acid SCHEMBL30128586 | 0.75 | PDPK1 (0.54) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| 2,6-Diaminopurine SCHEMBL4535059 | 0.75 | PDPK1 (0.79) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| 2,6-Diaminopurine SCHEMBL3238169 | 0.75 | PDPK1 (0.79) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| 2,6-Diaminopurine SCHEMBL30680639 | 0.75 | PDPK1 (0.79) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| SCHEMBL3915550 | 0.73 | TLR7 (0.34) | GDALMNAPNPTLR7 | |
| 2,6-Diaminopurine SCHEMBL8079030 | 0.73 | PDPK1 (0.77) | PDPK1GDACYP1A2CYP2C19HSD17B10 | |
| SCHEMBL15798376 | 0.73 | PDPK1 (0.44) | PDPK1GDACYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333418-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NOVO NORDISK AS (DK) | 2025-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333418-A1 | PURINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | CNR1, CNR2, P2RY1 | PDPK1 1004/4885GDA 909/4885CYP1A2 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.