Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621454 | 0.84 | LCLAT1 (0.42) | LCLAT1P2RX7PTGS1PTGS2POLB | |
| SCHEMBL20557311 | 0.83 | SMN1; SMN2 (0.43) | LCLAT1P2RX7POLBCYP1A2CNR1 | |
| SCHEMBL8403540 | 0.80 | BRD4 (0.62) | BRD4P2RX7PTGS1PTGS2POLB | |
| SCHEMBL2482068 | 0.79 | KDM4E (0.59) | LCLAT1KMT2AMEN1 | |
| SCHEMBL31357967 | 0.79 | KDM4E (0.59) | LCLAT1KMT2AMEN1 | |
| SCHEMBL7692521 | 0.77 | TSHR (0.43) | LCLAT1CYP3A4KMT2APARP1MEN1 | |
| SCHEMBL20557118 | 0.77 | TSHR (0.43) | LCLAT1POLBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18147143 | 0.76 | MAPT (0.59) | LCLAT1PTGS1PTGS2POLBKMT2A | |
| SCHEMBL31661294 | 0.76 | LCLAT1 (0.36) | LCLAT1POLBKMT2AMEN1 | |
| Acetic Acid SCHEMBL28994695 | 0.75 | TSHR (0.39) | LCLAT1POLBKMT2AMEN1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025226545-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-30 | — | — | WO | disclosed |