SCHEMBL317161

SCHEMBL317161

Fc1cc(F)c(F)c(F)c1F.O=COCl

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA4 P22748 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27298680 0.81 CA1 (0.39) CA1CA2CA4CA12CA7
SCHEMBL27737727 0.78 CA1 (0.40) CA1CA2CA4CA12CA7
Formamide SCHEMBL27556319 0.76 CA1 (0.44) CA1CA2CA4CA12CA7
SCHEMBL41646 0.74 CA1 (0.43) CA1CA2CA4CA12CA7
SCHEMBL7702552 0.74 CA1 (0.43) CA1CA2CA4CA12CA7
Formaldehyde SCHEMBL27280878 0.72 CA1 (0.43) CA1CA2CA4CA12CA7
SCHEMBL474389 0.71 INPPL1 (0.32) CES2CES1
SCHEMBL23589702 0.71 CA1 (0.41) CA1CA2CA4CA12CA7
Lithium SCHEMBL5688740 0.71 CA1 (0.41) CA1CA2CA4CA12CA7
SCHEMBL6470270 0.71 CA1 (0.41) CA1CA2CA4CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2590678-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION Fresenius Kabi Deutschland GmbH (DE) 2013-05-15 EP disclosed
EP-2590680-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION Fresenius Kabi Deutschland GmbH (DE) 2013-05-15 EP disclosed
WO-2012004007-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed
WO-2012004009-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed