SCHEMBL31716645

SCHEMBL31716645

Fc1ccc2cc(I)cnc2c1Br

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.42
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29801578 0.81 TET2 (0.44) TET2CCR1CCR5CCR8
SCHEMBL29496289 0.81 CCR1 (0.36) CCR1CCR5CCR8
SCHEMBL12483903 0.81 TET2 (0.44) TET2CCR1CCR5CCR8
SCHEMBL28724569 0.80 CCR1 (0.35) CCR1CCR5CCR8
SCHEMBL29698775 0.79 CCR1 (0.34) CCR1CCR5CCR8
SCHEMBL22846538 0.78 CCR1 (0.52) TET2CCR1CCR5CCR8
SCHEMBL29698830 0.75 KDM4E (0.51)
SCHEMBL1666214 0.74 TET2 (0.44) TET2CCR1CCR5CCR8
SCHEMBL22326638 0.73 TET2 (0.63) TET2
SCHEMBL26650883 0.73 TET2 (0.36) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025227032-A1 METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-10-30 WO disclosed