SCHEMBL31718260

SCHEMBL31718260

O=C1CCC(N2Cc3cc(OC4CC5CNCC5C4)ccc3C2=O)C(=O)N1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.62
▸ IKZF2 Q9UKS7 8/20 0.50
▸ CSNK1A1 P48729 1/20 0.49
▸ WIZ O95785 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20046262 0.92 CRBN (0.67) CRBNIKZF2CSNK1A1WIZ
SCHEMBL23350206 0.88 CRBN (0.64) CRBNIKZF2CSNK1A1WIZ
SCHEMBL20231488 0.88 CRBN (0.64) CRBNIKZF2CSNK1A1WIZ
SCHEMBL20231436 0.88 CRBN (0.67) CRBNIKZF2CSNK1A1WIZ
SCHEMBL24938481 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ
SCHEMBL24938496 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1
SCHEMBL24938848 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ
SCHEMBL24938463 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ
SCHEMBL24938470 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ
SCHEMBL24939176 0.87 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644382-A1 COMPOUND BASED ON SULFUR/OXYGEN SUBSTITUTED GLUTARIMIDE-BASED ISOINDOLINONE SKELETON AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2025-11-05 — — EP disclosed
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