SCHEMBL317183

SCHEMBL317183

O=[C]c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21931937 0.96
SCHEMBL9116623 0.96
SCHEMBL6130585 0.92
SCHEMBL17866497 0.87
SCHEMBL10729773 0.83 CA1 (0.32)
SCHEMBL6266936 0.81
SCHEMBL3774695 0.81
SCHEMBL8572304 0.78
SCHEMBL775531 0.76 SMN1; SMN2 (0.36)
SCHEMBL10701289 0.72 MAPK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945983-A Intermediate for preparing CDK4/6 active compound and preparation method thereof 创沐医药科技(上海)有限公司 2024-04-30 CN claimed
CN-117247359-A Dendrimer-like lipid compound, liposome, lipid complex, lipid nanoparticle and application thereof 中国科学院广州生物医药与健康研究院 2023-12-19 CN claimed
WO-2023236824-A1 DENDRON-LIKE LIPID COMPOUND, LIPOSOME, LIPID COMPLEX, AND LIPID NANOPARTICLE AND USE THEREOF 中国科学院广州生物医药与健康研究院 2023-12-14 WO claimed
CN-115947690-A Preparation method of indazole molecular building block and application of building block in drug synthesis 安徽医科大学 2023-04-11 CN claimed
US-11596716-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2023-03-07 US claimed
CN-115650874-A Method for synthesizing o-phenylenediamine compounds 西南大学 2023-01-31 CN claimed
CN-115340562-A Meso-amide-substituted 1,3,5, 7-tetramethyl-boron dipyrrole compound and preparation method and application thereof 复旦大学 2022-11-15 CN claimed
CN-114276247-A 1,5-enyne ester chiral compound and synthesis method thereof 华中师范大学 2022-04-05 CN claimed
US-20220059861-A1 Ion-selective membrane for redox flow batteries NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2022-02-24 US claimed
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US claimed
EP-0745065-A1 9-(SUBSTITUTED AMINO)-ALPHA-6-DEOXY-5-OXY TETRACYCLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS PFIZER INC. (US) 1996-12-04 EP claimed
EP-0725787-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-08-14 EP claimed
WO-1996006853-A1 ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF BECKMAN INSTRUMENTS, INC. (US) 1996-03-07 WO claimed
WO-1995022529-A1 9-(SUBSTITUTED AMINO)-ALPHA-6-DEOXY-5-OXY TETRACYCLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIBIOTICS PFIZER INC. (US) 1995-08-24 WO claimed
US-4868241-A POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE AMERICAN CYANAMID COMPANY (US) 1989-09-19 US claimed
WO-1988006732-A1 TAGGED BINDING REAGENTS AND METHODS FOR DETECTING TARGET ANALYTES ALLIED CORPORATION (US) 1988-09-07 WO claimed
US-4709016-A Molecular analytical release tags and their use in chemical analysis NORTHEASTERN UNIVERSITY (US) 1987-11-24 US claimed
EP-0231922-A2 Electron beam and X-ray resists AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed
US-4650750-A Method of chemical analysis employing molecular release tag compounds GIESE ROGER W (US) 1987-03-17 US claimed
US-4409397-A Asymmetric hydrogenation of tetra-substituted olefinic acids and derivatives SHELL OIL COMPANY (US) 1983-10-11 US claimed