Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.61 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.61 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5145795 | 0.89 | SMARCA2 (0.65) | SMARCA2SMARCA4MEN1KMT2APOLB | |
| SCHEMBL7933383 | 0.85 | SMARCA2 (0.59) | SMARCA2SMARCA4MEN1MAPTKMT2A | |
| SCHEMBL27481922 | 0.82 | SMARCA2 (0.57) | SMARCA2SMARCA4ALDH1A1KDM4EMEN1 | |
| SCHEMBL9599834 | 0.82 | SMARCA2 (0.86) | SMARCA2SMARCA4ALDH1A1HTTNPC1 | |
| SCHEMBL22584967 | 0.81 | AR (0.52) | GSTO1ALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL2191563 | 0.81 | SMARCA2 (0.60) | SMARCA2SMARCA4ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL17796335 | 0.81 | HPGD (0.58) | SMARCA2SMARCA4ALDH1A1SMN1; SMN2NOD2 | |
| SCHEMBL9600748 | 0.81 | SMARCA2 (0.63) | SMARCA2SMARCA4ALDH1A1HTTKDM4E | |
| SCHEMBL1400789 | 0.80 | SMARCA2 (0.68) | SMARCA2SMARCA4 | |
| SCHEMBL9278345 | 0.79 | SMARCA2 (0.65) | SMARCA2SMARCA4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025229046-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) | 2025-11-06 | — | — | WO | disclosed |
| EP-4644375-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | Molius Saglik Teknolojileri Anonim Sirketi (TR) | 2025-11-05 | — | — | EP | disclosed |