Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.50 |
| ▸ | FLT1 | P17948 | 6/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | STK10 | O94804 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | INSR | P06213 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | YES1 | P07947 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31719507 | 0.93 | KDR (0.42) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719135 | 0.92 | KDR (0.60) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719067 | 0.92 | KDR (0.55) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719055 | 0.90 | KDR (0.49) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719570 | 0.89 | KDR (0.42) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL3091098 | 0.88 | KDR (0.55) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719485 | 0.87 | KDR (0.51) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719309 | 0.87 | KDR (0.55) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719439 | 0.86 | KDR (0.50) | KDRPDGFRBFLT1TGFBR1ACVR1 | |
| SCHEMBL31719438 | 0.86 | KDR (0.50) | KDRPDGFRBFLT1TGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4644390-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | Beyang Therapeutics Co., Ltd. (CN) | 2025-11-05 | — | — | EP | disclosed |