Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 3/20 | 0.41 |
| ▸ | CDK8 | P49336 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341599 | 0.86 | IRAK4 (0.43) | CCNCCDK8MAPTKMORXFP1 | |
| SCHEMBL31721208 | 0.81 | PDE1C (0.46) | CCNCCDK8KDM4EALDH1A1GAA | |
| SCHEMBL19465607 | 0.78 | KDM4E (0.47) | MGAMCCNCCDK8KDM4ETDP1 | |
| SCHEMBL31721248 | 0.78 | CYP1A2 (0.53) | KDM4ETSHRALDH1A1POLBGAA | |
| SCHEMBL31749124 | 0.77 | CDK8 (0.36) | CCNCCDK8KDM4EALDH1A1GAA | |
| SCHEMBL19465591 | 0.75 | KDM4E (0.53) | MGAMKDM4ETDP1ALOX15TSHR | |
| SCHEMBL22453989 | 0.74 | MGAM (0.44) | MGAMCCNCCDK8KDM4ETDP1 | |
| SCHEMBL29549763 | 0.74 | MGAM (0.44) | MGAMCCNCCDK8KDM4ETDP1 | |
| SCHEMBL25382823 | 0.73 | NOTUM (0.39) | CDK8GAAMAPTRAB9AKMO | |
| SCHEMBL14645392 | 0.73 | MGAM (0.43) | MGAMCCNCCDK8KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231152-A1 | COMPOUNDS AND METHODS FOR RESTORING BETA-ADRENERGIC RECEPTOR FUNCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2025-11-06 | — | — | WO | disclosed |