Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645392 | 0.81 | MGAM (0.43) | KDM4EKMT2AMEN1RAB9AMAPT | |
| SCHEMBL31721208 | 0.75 | PDE1C (0.46) | MAPK1KDM4EPTGER4ALDH1A1KMT2A | |
| SCHEMBL29550054 | 0.75 | KDM4E (0.46) | MAPK1KDM4EPTGER4KMT2AMEN1 | |
| SCHEMBL23529965 | 0.75 | KDM4E (0.46) | MAPK1KDM4EPTGER4KMT2AMEN1 | |
| SCHEMBL31358062 | 0.75 | NR1H2 (0.39) | MAPK1PTGER4KMT2AMEN1 | |
| SCHEMBL24174887 | 0.74 | MAPK1 (0.42) | MAPK1KDM4EPTGER4ALDH1A1KMT2A | |
| SCHEMBL19932639 | 0.74 | KMT2A (0.43) | MAPK1KDM4EALDH1A1KMT2ACYP1A2 | |
| SCHEMBL30540611 | 0.74 | NQO2 (0.42) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL15687076 | 0.74 | NOTUM (0.43) | PTGER4MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL31403612 | 0.73 | MAPK1 (0.41) | MAPK1KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025231152-A1 | COMPOUNDS AND METHODS FOR RESTORING BETA-ADRENERGIC RECEPTOR FUNCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2025-11-06 | — | — | WO | disclosed |