Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.53 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22512063 | 0.97 | CRBN (0.57) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL29439947 | 0.97 | CRBN (0.57) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL23226003 | 0.96 | CRBN (0.56) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL31722330 | 0.94 | CRBN (0.60) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL29440022 | 0.91 | CRBN (0.58) | CRBNCSNK1A1GSPT1 | |
| SCHEMBL22512119 | 0.91 | CRBN (0.58) | CRBNCSNK1A1GSPT1 | |
| SCHEMBL20231302 | 0.90 | CRBN (0.61) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30046480 | 0.90 | CRBN (0.61) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27091431 | 0.89 | CRBN (0.60) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL22511704 | 0.88 | CRBN (0.55) | CRBNCSNK1A1IKZF2GSPT1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228947-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF INDUCING DEGRADATION OF POLO-LIKE KINASE1 | CROSSFIRE ONCOLOGY B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |