Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CASP1 | P29466 | 2/20 | 0.73 |
| ▸ | CASP7 | P55210 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22284778 | 1.00 | MAPT (0.73) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31723128 | 0.91 | MAPT (0.60) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28425356 | 0.91 | MAPT (0.60) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31723130 | 0.87 | CA1 (0.60) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22284795 | 0.87 | CA1 (0.60) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31723129 | 0.87 | KDM4E (0.56) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL31723152 | 0.86 | MEN1 (0.72) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28425332 | 0.86 | MEN1 (0.72) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30667444 | 0.84 | MAPT (1.00) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5138212 | 0.84 | MAPT (1.00) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699174-B1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2025-11-12 | — | — | EP | claimed |