SCHEMBL31723254

SCHEMBL31723254

COc1ccc(Nc2cc(Cl)cc(N)c2C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
GAA P10253 4/20 0.53
RAB9A P51151 4/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 2/20 0.53
THRB P10828 2/20 0.53
RECQL P46063 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 2/20 0.53
HTT P42858 1/20 0.53
MMP14 P50281 1/20 0.53
NR4A1 P22736 1/20 0.49
MAPK1 P28482 2/20 0.47
NPC1 O15118 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
SLC2A1 P11166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22232049 1.00 MAPT (0.53) MAPTGAARAB9AMEN1KMT2A
SCHEMBL4933129 0.81 MAPT (0.59) MAPTGAARAB9AMEN1KMT2A
SCHEMBL4928513 0.81 MAPT (0.59) MAPTGAARAB9AMEN1KMT2A
SCHEMBL22232365 0.81 GAA (0.50) MAPTGAAMEN1KMT2AKDM4E
SCHEMBL22232200 0.79 BACE2 (0.41) MAPTGAARAB9AMEN1KMT2A
SCHEMBL31723248 0.79 BACE2 (0.41) MAPTGAARAB9AMEN1KMT2A
SCHEMBL29454056 0.79 BACE2 (0.41) MAPTGAARAB9AMEN1KMT2A
SCHEMBL4933031 0.76 MAPT (0.57) MAPTGAARAB9AMEN1KMT2A
SCHEMBL22232357 0.76 MAPT (0.53) MAPTGAARAB9AMEN1KMT2A
SCHEMBL29454142 0.76 MAPT (0.53) MAPTGAARAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647426-A2 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2025-11-12 EP claimed