Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.44 |
| ▸ | CCND3 | P30281 | 2/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879043 | 0.96 | PTPN11 (0.52) | PTPN11MAPK3MAPK1CDK4CCND3 | |
| SCHEMBL24879474 | 0.96 | PTPN11 (0.53) | PTPN11MAPK3MAPK1CDK4CCND3 | |
| SCHEMBL24878927 | 0.94 | PTPN11 (0.54) | PTPN11MAPK3MAPK1 | |
| SCHEMBL31723348 | 0.93 | PTPN11 (0.51) | PTPN11MAPK3MAPK1 | |
| SCHEMBL27453103 | 0.92 | PTPN11 (0.54) | PTPN11MAPK3MAPK1 | |
| SCHEMBL30987302 | 0.92 | PTPN11 (0.51) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879308 | 0.92 | PTPN11 (0.53) | PTPN11MAPK3MAPK1CDK4CCND3 | |
| SCHEMBL24879187 | 0.89 | PTPN11 (0.51) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24878881 | 0.89 | PTPN11 (0.53) | PTPN11MAPK3MAPK1CDK4CCND3 | |
| SCHEMBL24879146 | 0.89 | PTPN11 (0.52) | PTPN11MAPK3MAPK1CDK4CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |