Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24878908 | 0.87 | PTPN11 (0.48) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL31723383 | 0.85 | PTPN11 (0.63) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27453046 | 0.81 | PTPN11 (0.47) | PTPN11MAPK3MAPK1 | |
| SCHEMBL27453838 | 0.79 | PTPN11 (0.44) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27453840 | 0.79 | PTPN11 (0.45) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27240712 | 0.78 | PTPN11 (0.44) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27216092 | 0.78 | PTPN11 (0.43) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL29281493 | 0.77 | PTPN11 (0.48) | PTPN11 | |
| SCHEMBL16915558 | 0.77 | PTPN11 (1.00) | PTPN11KCNH2 | |
| SCHEMBL16926370 | 0.77 | PTPN11 (1.00) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |