Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.64 |
| ▸ | ARG2 | P78540 | 4/20 | 0.57 |
| ▸ | ARG1 | P05089 | 3/20 | 0.57 |
| ▸ | NOS2 | P35228 | 6/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727385 | 1.00 | GSR (0.64) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL12594195 | 0.98 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL9827768 | 0.98 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL4390305 | 0.98 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL27706580 | 0.98 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL9827465 | 0.98 | GSR (0.61) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL27805765 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL1764073 | 0.91 | GSR (0.58) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL1764070 | 0.91 | GSR (0.58) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL29268443 | 0.87 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724053-A | Immunotherapy targeting SOX2 antigen | 弗雷德哈钦森癌症中心 | 2023-09-08 | — | — | CN | disclosed |
| EP-1640380-B1 | HISTONE DEACETYLASE INHIBITOR AND PROCESS FOR PRODUCING THE SAME | RIKEN (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7662778-B2 | a compound containing cyclic tetrapeptide coupled to amide, ester, ketone groups; apoptosis and cell differentiation inducer; cancer metastasis and angiogenesis inhibitor; catalytic hydrogenation, acid treatment, fluoride anion treatment, or hydrolysis for deblocking; coupling cyclic tertrapeptide | RIKEN (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20070185071-A1 | Histone deacetylase inhibitor and process for producing the same | RIKEN (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1640380-A1 | HISTONE DEACETYLASE INHIBITOR AND PROCESS FOR PRODUCING THE SAME | Riken (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185071-A1 | Histone deacetylase inhibitor and process for producing the same | HDAC1, HDAC4, HDAC5 | GSR 4199/4885ARG2 1377/4885ARG1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.