⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991938 | 0.95 | SMN1; SMN2 (0.61) | — | |
| SCHEMBL269018 | 0.93 | EPHX1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL3512220 | 0.93 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL23475863 | 0.93 | EPHX1 (0.61) | — | |
| SCHEMBL22546754 | 0.93 | EPHX1 (0.61) | — | |
| SCHEMBL23475876 | 0.93 | EPHX1 (0.61) | — | |
| Hydrochloric Acid SCHEMBL7307604 | 0.91 | EPHX1 (0.59) | — | |
| SCHEMBL16853215 | 0.90 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL3135300 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL1996186 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346567-A1 | SUBSTITUTED PYRIDINE AND PHENYL COMPOUNDS | PFIZER INC. (US) | 2025-11-13 | — | — | US | disclosed |