Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 13/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 2/20 | 0.53 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974433 | 0.98 | TFPI (0.60) | TFPIBACE1BACE2CTSDPTH1R | |
| SCHEMBL30839569 | 0.97 | TFPI (0.56) | TFPIBACE1BACE2CTSD | |
| SCHEMBL29591183 | 0.93 | TFPI (0.67) | TFPIBACE1BACE2CTSD | |
| SCHEMBL30097927 | 0.92 | TFPI (0.57) | TFPIPTH1R | |
| SCHEMBL31031480 | 0.91 | TFPI (0.55) | TFPI | |
| SCHEMBL30421823 | 0.91 | TFPI (0.61) | TFPIBACE1BACE2CTSD | |
| SCHEMBL29622911 | 0.90 | TFPI (0.62) | TFPIBACE1CTSD | |
| SCHEMBL31257037 | 0.90 | BACE1 (0.60) | TFPIBACE1BACE2CTSD | |
| SCHEMBL31454246 | 0.90 | TFPI (0.56) | TFPIBACE1BACE2CTSD | |
| SCHEMBL30543038 | 0.90 | TFPI (0.54) | TFPIBACE1PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250345387-A1 | CORONAVIRUS THERAPEUTICS AND TREATMENT METHODS | HAMILTON DOUGLAS A (US) | 2025-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250345387-A1 | CORONAVIRUS THERAPEUTICS AND TREATMENT METHODS | SARS1, ACE2, TMPRSS2 | TFPI 38/4885BACE1 828/4885BACE2 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.