Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725488 | 0.82 | AURKA (0.47) | LRRK2ULK1HDAC3HDAC1HDAC2 | |
| SCHEMBL12149236 | 0.80 | LRRK2 (0.47) | TRPV1LRRK2CYP1A2ULK1 | |
| SCHEMBL27228448 | 0.76 | GAA (0.40) | TRPV1LRRK2CYP1A2ULK1RPS6KA5 | |
| SCHEMBL21374216 | 0.73 | XPO1 (0.40) | TRPV1LRRK2CYP1A2ULK1 | |
| SCHEMBL11916180 | 0.73 | LRRK2 (0.42) | TRPV1LRRK2CYP1A2 | |
| SCHEMBL29141596 | 0.72 | CCNK (0.60) | ULK1 | |
| SCHEMBL29141599 | 0.72 | CCNK (0.60) | ULK1 | |
| SCHEMBL30772306 | 0.72 | CCNK (0.60) | ULK1 | |
| SCHEMBL13323758 | 0.70 | TRPV1 (0.39) | TRPV1LRRK2CYP1A2ULK1HDAC3 | |
| SCHEMBL22997711 | 0.70 | TRPV1 (0.37) | TRPV1LRRK2CYP1A2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235687-A1 | LRRK2 INHIBITORS | Brenig Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | disclosed |