Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 6/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 6/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738272 | 0.87 | NR1H2 (0.39) | NR1H2KDM1AXIAPBIRC2GPR119 | |
| SCHEMBL29713511 | 0.86 | NR1H2 (0.39) | NR1H2KDM1AXIAPBIRC2 | |
| SCHEMBL15649736 | 0.86 | NR1H2 (0.39) | NR1H2KDM1AXIAPBIRC2 | |
| SCHEMBL13732154 | 0.86 | NR1H2 (0.39) | NR1H2KDM1AXIAPBIRC2CYP11B2 | |
| SCHEMBL13733056 | 0.85 | NR1H2 (0.38) | NR1H2KDM1AXIAPBIRC2GPR119 | |
| SCHEMBL31700413 | 0.85 | NR1H2 (0.38) | NR1H2KDM1AXIAPBIRC2GPR119 | |
| SCHEMBL31368981 | 0.85 | NR1H2 (0.38) | NR1H2KDM1AXIAPBIRC2GPR119 | |
| SCHEMBL13732881 | 0.84 | XIAP (0.45) | NR1H2XIAPBIRC2 | |
| SCHEMBL13732818 | 0.82 | NR1H2 (0.36) | NR1H2KDM1AXIAPBIRC2USP30 | |
| SCHEMBL31725773 | 0.81 | USP30 (0.45) | NR1H2XIAPBIRC2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235719-A1 | DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY | VIIV HEALTHCARE COMPANY (US) | 2025-11-13 | — | — | WO | disclosed |