Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698056 | 1.00 | NPC1 (0.63) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL31361425 | 0.94 | BCHE (0.60) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL3239903 | 0.94 | BCHE (0.60) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL584781 | 0.90 | SLC2A1 (0.56) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL30280404 | 0.90 | SLC2A1 (0.56) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL31040308 | 0.89 | NPC1 (0.52) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL30027542 | 0.89 | NPC1 (0.52) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL1322956 | 0.88 | KDM4E (0.64) | NPC1RAB9AMEN1KMT2ABCHE | |
| SCHEMBL21377514 | 0.87 | NPC1 (0.63) | NPC1RAB9APOLBKDM4EAPP | |
| SCHEMBL6035606 | 0.86 | MEN1 (0.60) | NPC1RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235719-A1 | DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY | VIIV HEALTHCARE COMPANY (US) | 2025-11-13 | — | — | WO | disclosed |