SCHEMBL31726780

SCHEMBL31726780

CC(C)(C)OC(=O)N1CCC2(CC1)CCN(c1ccc([C@H]3CCC(=O)NC3=O)cc1)C2

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.58
▸ CRBN Q96SW2 11/20 0.58
▸ GPR119 Q8TDV5 6/20 0.44
▸ CYP11B2 P19099 1/20 0.41
▸ HRH3 Q9Y5N1 1/20 0.41
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30768423 0.95 CRBN (0.57) DDB1CRBNGPR119CYP11B2POLB
SCHEMBL30831066 0.95 DDB1 (0.59) DDB1CRBNGPR119POLB
SCHEMBL29680902 0.94 DDB1 (0.58) DDB1CRBNGPR119CYP11B2POLB
SCHEMBL31726711 0.94 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL29680886 0.94 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL26641205 0.91 CRBN (0.59) DDB1CRBNGPR119POLB
SCHEMBL24880592 0.88 CRBN (0.62) DDB1CRBNGPR119POLB
SCHEMBL21876964 0.88 DDB1 (0.67) DDB1CRBNGPR119
SCHEMBL23301226 0.88 DDB1 (0.67) DDB1CRBNGPR119
SCHEMBL30830936 0.87 DDB1 (0.52) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235363-A1 CYCLIN-DEPENDENT KINASE 4 DEGRADERS BLUEPRINT MEDICINES CORPORATION (US) 2025-11-13 — — WO disclosed
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