Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423558 | 0.98 | MDM2 (0.46) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL30731420 | 0.98 | MDM2 (0.46) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL22690415 | 0.98 | MDM2 (0.46) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL22690416 | 0.98 | MDM2 (0.46) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL16424792 | 0.98 | MDM2 (0.46) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL31726487 | 0.94 | MDM2 (0.43) | MDM2CA1CA2TLR2TLR1 | |
| SCHEMBL31727026 | 0.91 | MDM2 (0.43) | MDM2CASP3CA1CA2TLR2 | |
| SCHEMBL17550375 | 0.91 | MDM2 (0.44) | MDM2CA1CA2TLR2TLR1 | |
| SCHEMBL13401516 | 0.91 | MDM2 (0.52) | MDM2CA1CA2TLR2TLR1 | |
| SCHEMBL16325412 | 0.91 | MDM2 (0.52) | MDM2CA1CA2TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235686-A1 | FLUOROCAMPTOTHECIN COMPOUNDS, CONJUGATES, AND METHODS THEREOF | Aarvik Therapeutics, Inc. (US) | 2025-11-13 | — | — | WO | disclosed |