Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727621 | 0.77 | TDP1 (0.44) | TDP1GSK3BBACE1IDO1KDM4E | |
| SCHEMBL31727742 | 0.72 | TDP1 (0.41) | TDP1GSK3BBACE1IDO1KDM4E | |
| SCHEMBL18025746 | 0.70 | MAPT (0.49) | TDP1GSK3BIDO1KDM4EALDH1A1 | |
| SCHEMBL31726983 | 0.70 | TDP1 (0.40) | TDP1GSK3BBACE1IDO1KDM4E | |
| SCHEMBL4164922 | 0.66 | NOTUM (0.31) | GSK3B | |
| SCHEMBL1884372 | 0.66 | GSK3B (0.46) | TDP1GSK3BIDO1GAAKMT2A | |
| SCHEMBL30965334 | 0.66 | KMT2A (0.48) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL29242297 | 0.66 | KMT2A (0.48) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL8873308 | 0.66 | MAPT (0.39) | IDO1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL14621115 | 0.65 | CDC7 (0.36) | GSK3BIDO1MAPTRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235362-A1 | INDOLINONE COMPOUNDS AS KCa3.1 POTASSIUM CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC (US) | 2025-11-13 | — | — | WO | disclosed |