Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728390 | 0.84 | MAPT (0.40) | MAP4K4PIK3CD | |
| SCHEMBL31728922 | 0.83 | PIK3CD (0.33) | MAP4K4MPOPIK3CD | |
| SCHEMBL31729241 | 0.74 | IDO1 (0.36) | IDO1MAP4K4PIK3CD | |
| SCHEMBL31728528 | 0.74 | IDO1 (0.36) | IDO1PTPN11MAP4K4PIK3CD | |
| SCHEMBL31728459 | 0.70 | PIK3CD (0.31) | IDO1MPOPIK3CD | |
| SCHEMBL31729201 | 0.69 | EGFR (0.40) | PIK3CD | |
| SCHEMBL31728730 | 0.65 | PDE5A (0.36) | IDO1MAP4K4PIK3CD | |
| SCHEMBL31728529 | 0.65 | SRC (0.39) | MAP4K4PIK3CD | |
| SCHEMBL31727897 | 0.63 | LIMK1 (0.36) | IDO1MAP4K4PIK3CD | |
| SCHEMBL31728766 | 0.62 | PIK3CD (0.38) | IDO1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |