Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.36 |
| ▸ | PRKDC | P78527 | 5/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | HCK | P08631 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728529 | 0.83 | SRC (0.39) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31729240 | 0.82 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31729241 | 0.79 | IDO1 (0.36) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31728766 | 0.75 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31728394 | 0.74 | CLK1 (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31727897 | 0.73 | LIMK1 (0.36) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31729134 | 0.73 | GSK3B (0.41) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31727874 | 0.72 | CLK1 (0.38) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31728359 | 0.72 | EPHB4 (0.36) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC | |
| SCHEMBL31728598 | 0.70 | LIMK1 (0.41) | PIK3CDPIK3CAPIK3CGPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |