Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 6/20 | 0.35 |
| ▸ | PI4KA | P42356 | 3/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CSK | P41240 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728557 | 0.69 | RPS6KA1 (0.31) | — | |
| SCHEMBL29728040 | 0.66 | PI4KA (0.48) | MAP4K4LIMK1PI4KAPI4K2BPI4K2A | |
| SCHEMBL31291221 | 0.66 | MAP4K4 (0.36) | MAP4K4 | |
| SCHEMBL20399046 | 0.66 | PI4KA (0.48) | MAP4K4LIMK1PI4KAPI4K2BPI4K2A | |
| SCHEMBL31291220 | 0.66 | MAP4K4 (0.36) | MAP4K4 | |
| SCHEMBL30639393 | 0.66 | LIMK1 (0.49) | MAP4K4LIMK1PI4KAPI4K2BPI4K2A | |
| SCHEMBL30639391 | 0.66 | LIMK1 (0.63) | MAP4K4LIMK1PI4KAPI4K2BPI4K2A | |
| SCHEMBL30639390 | 0.65 | PI4KA (0.49) | LIMK1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL245963 | 0.65 | MAP4K4 (0.43) | MAP4K4LIMK1CDC7CLK1DBF4 | |
| SCHEMBL30639400 | 0.64 | LIMK1 (0.46) | MAP4K4LIMK1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |